BDBM150548 US10238633, Example 222::US8987249, 222::US9713606, 222

SMILES CS(=O)(=NC#N)c1cccc(c1)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1

InChI Key InChIKey=LPAPVHRQNZAJHB-PVEGDPQMSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 150548   

TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM150548(US10238633, Example 222 | US8987249, 222 | US97136...)
Affinity DataIC50:  2.20nMpH: 6.0 T: 2°CAssay Description:Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 6007270). The substrate Gly-Arg-AMC was from Biotrend (Prod....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin K(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM150548(US10238633, Example 222 | US8987249, 222 | US97136...)
Affinity DataIC50:  1.70E+3nMpH: 3.5 T: 2°CAssay Description:Materials: Microtiterplates (Optiplate-384 F were purchased from PerkinElmer (Prod. No. 6007270). The substrate Z-Gly-Pro-Arg-AMC was from Biomol (Pr...More data for this Ligand-Target Pair
In DepthDetails US Patent