BDBM15429 1,3-dimethyl-5-[2-(thiophen-2-yl)-4-[3-(trifluoromethoxy)phenyl]-1H-imidazol-5-yl]-2,3-dihydro-1H-1,3-benzodiazol-2-one::benzimidazolone 12o

SMILES Cn1c2ccc(cc2n(C)c1=O)-c1nc([nH]c1-c1cccc(OC(F)(F)F)c1)-c1cccs1

InChI Key InChIKey=FYXYFFJEYBXPSH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15429   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer

LigandPNGBDBM15429(1,3-dimethyl-5-[2-(thiophen-2-yl)-4-[3-(trifluorom...)
Affinity DataIC50:  1.58E+4nMpH: 7.2 T: 2°CAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed