BDBM15436 1,3-dimethyl-5-{4-[3-(propan-2-yl)phenyl]-2-(thiophen-2-yl)-1H-imidazol-5-yl}-2,3-dihydro-1H-1,3-benzodiazol-2-one::benzimidazolone 12v

SMILES CC(C)c1cccc(c1)-c1[nH]c(nc1-c1ccc2n(C)c(=O)n(C)c2c1)-c1cccs1

InChI Key InChIKey=VLZWWLJWKCJAEF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15436   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer

LigandPNGBDBM15436(1,3-dimethyl-5-{4-[3-(propan-2-yl)phenyl]-2-(thiop...)
Affinity DataIC50: >3.20E+4nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed