BDBM15442 1,3-diethyl-5-[3-(4-fluoro-3-methylphenyl)-1H-pyrazol-4-yl]-2,3-dihydro-1H-1,3-benzodiazol-2-one::benzimidazolone 16a

SMILES CCn1c2ccc(cc2n(CC)c1=O)-c1c[nH]nc1-c1ccc(F)c(C)c1

InChI Key InChIKey=GOYIWGNKBULYBS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15442   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer

LigandPNGBDBM15442(1,3-diethyl-5-[3-(4-fluoro-3-methylphenyl)-1H-pyra...)
Affinity DataIC50:  30nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed