BDBM15443 1,3-diethyl-5-{3-[3-(trifluoromethyl)phenyl]-1H-pyrazol-4-yl}-2,3-dihydro-1H-1,3-benzodiazol-2-one::benzimidazolone 16b

SMILES CCn1c2ccc(cc2n(CC)c1=O)-c1c[nH]nc1-c1cccc(c1)C(F)(F)F

InChI Key InChIKey=KSPOJZNAWMACAN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15443   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer

LigandPNGBDBM15443(1,3-diethyl-5-{3-[3-(trifluoromethyl)phenyl]-1H-py...)
Affinity DataIC50:  60nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed