BDBM154574 N-(2H-1,3-benzodioxol-5-ylmethyl)-1-[(1S)-1-(naphthalen-1-yl)ethyl]piperidine-4-carboxamide (I-4)::med.21724, Compound 166

SMILES C[C@H](N1CCC(CC1)C(=O)NCc1ccc2OCOc2c1)c1cccc2ccccc12

InChI Key InChIKey=IVXBCFLWMPMSAP-SFHVURJKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 154574   

TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
University of Bonn

LigandPNGBDBM154574(N-(2H-1,3-benzodioxol-5-ylmethyl)-1-[(1S)-1-(napht...)
Affinity DataIC50:  560nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
University of Illinois At Chicago

LigandPNGBDBM154574(N-(2H-1,3-benzodioxol-5-ylmethyl)-1-[(1S)-1-(napht...)
Affinity DataIC50:  2.26E+3nMpH: 7.5Assay Description:done in a single pass in black 384-well plates (Matrix Technologies). The SARS-PLpro enzyme (20 nM final concentration) was prepared in an assay buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed