BDBM156119 US9018214, 170

SMILES C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccccc4)cc23)[C@H](CN1)C(=O)N(C)C

InChI Key InChIKey=WVYSFJMJSGWZGD-XMSQKQJNSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 156119   

TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM156119(US9018214, 170)
Affinity DataIC50:  180nMpH: 7.5 T: 2°CAssay Description:Modified SMAC peptides and compounds were tested for their ability to displace the fluorescent tracer from either XIAP, clAP-1 or clAP-2. BIR3 domain...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM156119(US9018214, 170)
Affinity DataIC50:  250nMAssay Description:Inhibition of SMAC-derived peptide abuRPFK (5 and 6FAM)-amide interaction with XIAP BIR3 domain (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM156119(US9018214, 170)
Affinity DataIC50:  11nMpH: 7.5 T: 2°CAssay Description:Modified SMAC peptides and compounds were tested for their ability to displace the fluorescent tracer from either XIAP, clAP-1 or clAP-2. BIR3 domain...More data for this Ligand-Target Pair
In DepthDetails US Patent