BDBM158225 US9029370, 18

SMILES Fc1ccc(cc1)-n1cc(cn1)C(=O)Nc1ccc(cc1Cl)C1CNCCO1

InChI Key InChIKey=SFFQUAOVCNLRED-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 158225   

TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM158225(US9029370, 18)
Affinity DataKi:  1.20nM ΔG°:  -12.7kcal/molepH: 7.4 T: 2°CAssay Description:Membrane Preparation and Radioligand Binding. HEK-293 cells stably expressing mouse TAA 1 were maintained at 37 C and 5% C02 in DMEM high glucose med...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Rattus norvegicus (Rat))
Hoffmann-La Roche

US Patent
LigandPNGBDBM158225(US9029370, 18)
Affinity DataKi:  3.30nM ΔG°:  -12.0kcal/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat inac...More data for this Ligand-Target Pair
In DepthDetails US Patent