BDBM158299 US9029370, 93
SMILES FC(F)Oc1ccc(cc1)-n1cc(cn1)C(=O)Nc1ccc([C@@H]2CNCCO2)c(Cl)c1
InChI Key InChIKey=QIOOAVAQJJQTIU-IBGZPJMESA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 158299
Affinity DataKi: 0.5nM ΔG°: -13.2kcal/molepH: 7.4 T: 2°CAssay Description:Membrane Preparation and Radioligand Binding. HEK-293 cells stably expressing mouse TAA 1 were maintained at 37 C and 5% C02 in DMEM high glucose med...More data for this Ligand-Target Pair
Affinity DataKi: 1.20nM ΔG°: -12.7kcal/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat inac...More data for this Ligand-Target Pair