BDBM158542 US9034866, 17

SMILES NC(=O)c1cn2CCOc3cc(F)c(cc3-c2n1)C#CC1(O)CCC1

InChI Key InChIKey=NBQFUXCJBIMUNM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 158542   

TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM158542(US9034866, 17)
Affinity DataKi:  10nMpH: 7.2Assay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5'-triphosphate (ATP) was monitored u...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM158542(US9034866, 17)
Affinity DataKi:  20nMAssay Description:Inhibition of NIK (unknown origin) after 1 to 2 hrs by ADP-FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed