BDBM158600 US9034866, 75

SMILES CC(O)(CF)C#Cc1cc2-c3nc(cn3CCOc2cc1F)C(N)=O

InChI Key InChIKey=WXSRVVZLLPDJNW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 158600   

TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM158600(US9034866, 75)
Affinity DataKi:  8nMpH: 7.2Assay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5'-triphosphate (ATP) was monitored u...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM158600(US9034866, 75)
Affinity DataKi:  8.70nMAssay Description:Inhibition of NIK (unknown origin) after 1 to 2 hrs by ADP-FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed