BDBM160852 US10093655, Example 22::US11014909, Example 22::US9107923, 22

SMILES CCc1c(-c2ccc(Oc3ncccc3Cl)cc2)n(C)c(=O)[nH]c1=O

InChI Key InChIKey=WHKALTOOONYAIQ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 160852   

TargetD(1A) dopamine receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM160852(US10093655, Example 22 | US11014909, Example 22 | ...)
Affinity DataKi:  82.7nMAssay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., Dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM160852(US10093655, Example 22 | US11014909, Example 22 | ...)
Affinity DataKi:  82.7nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM160852(US10093655, Example 22 | US11014909, Example 22 | ...)
Affinity DataKi:  82.7nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In DepthDetails US Patent