BDBM161088 US9108951, 100::US9394276, 100::US9725435, 100
SMILES OC(=O)c1ccc(NC(=O)C2N(CCc3ncc(NC(=O)Nc4ccc(Cl)cc4)cc23)C(=O)\C=C\c2cc(Cl)ccc2-n2cnnn2)cc1
InChI Key InChIKey=GIIMCXNADXNBEK-KGVSQERTSA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 161088
Affinity DataKi: 258nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of the coagulation factors XIa, Vila, IXa, Xa, Xlla, plasma kallikrein or throm...More data for this Ligand-Target Pair
Affinity DataKi: 258nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Affinity DataKi: 258nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair