BDBM161331 US10087143, Compound 116::US10738009, Compound 116::US11673864, Compound 116::US9051270, 116::US9758483, Compound 116

SMILES CC(C)CCOc1cc(ccc1C(=O)Nc1cc[nH]c(=O)c1)C(F)(F)F

InChI Key InChIKey=KICOFBPOACPQPG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 161331   

TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM161331(US10087143, Compound 116 | US10738009, Compound 11...)
Affinity DataIC50:  488nMAssay Description:Sodium channels are voltage-dependent proteins that can be activated by inducing membrane voltage changes by applying electric fields. The electrical...More data for this Ligand-Target Pair
In DepthDetails US Patent