BDBM161463 US10124003, Ref. Ex. Compound 4::US10835536, Ref. Ex. Comp 4::US10894048, Ref. Ex Comp. 4::US9108973, Ref 4

SMILES CC(C)c1cc(cc(c1)C(C)C)C#Cc1nn([C@H]2CCN(C2)C(=O)\C=C\CN(C)C)c2ncnc(N)c12

InChI Key InChIKey=HCCDWYKZANPJBR-UROCCOEBSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 161463   

TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161463(US10124003, Ref. Ex. Compound 4 | US10835536, Ref....)
Affinity DataIC50: >1.00E+4nMpH: 7.5 T: 2°CAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161463(US10124003, Ref. Ex. Compound 4 | US10835536, Ref....)
Affinity DataIC50: >1.00E+4nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161463(US10124003, Ref. Ex. Compound 4 | US10835536, Ref....)
Affinity DataIC50: >1.00E+4nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161463(US10124003, Ref. Ex. Compound 4 | US10835536, Ref....)
Affinity DataIC50: >1.00E+4nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails US Patent