BDBM161988 US9669028, 19 5-(3-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)-N-(1-methylpiperidin-4-yl)pyrimidin-4-amine

SMILES CN1CCC(CC1)Nc1ncncc1-c1cnc2[nH]nc(C)c2c1

InChI Key InChIKey=RZVKYENOMHNABF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 161988   

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Homo sapiens (Human))
Arrien Pharmaceuticals

US Patent
LigandPNGBDBM161988(US9669028, 19 5-(3-methyl-1H-pyrazolo[3,4-b]pyridi...)
Affinity DataIC50: >500nMAssay Description:Procedure: Enzyme was incubated with substrate peptide in reaction buffer in the presence and absence of test compounds or Staurosporine. All additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Arrien Pharmaceuticals

US Patent
LigandPNGBDBM161988(US9669028, 19 5-(3-methyl-1H-pyrazolo[3,4-b]pyridi...)
Affinity DataIC50: >500nMAssay Description:Procedure: Enzyme was incubated with substrate peptide in reaction buffer in the presence and absence of test compounds or Staurosporine. All additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent