BDBM163639 Methyl 2({[(6ethyl2oxo1,2dihydroquinolin3yl)methyl](2 hydroxyethyl)carbamothioyl}amino)benzoate (Inh 4)::US9334288, 6

SMILES CCc1ccc2[nH]c(=O)c(CN(CCO)C(=S)Nc3ccccc3C(=O)OC)cc2c1

InChI Key InChIKey=HZDIMQJXHLIPKQ-UHFFFAOYSA-N

Data  3 KI  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 163639   

TargetBeta-glucuronidase(Escherichia coli (Enterobacteria))
University of North Carolina At Chapel Hill

LigandPNGBDBM163639(Methyl 2({[(6ethyl2oxo1,2dihydroquinolin3yl)methyl...)
Affinity DataKi:  1.40E+3nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 無 assay buffer, 5 無 inhibitor solution, 5 無 of 10 nM enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-galactosidase [V151I,I185V](Clostridium perfringens (Firmicutes))
University of North Carolina At Chapel Hill

LigandPNGBDBM163639(Methyl 2({[(6ethyl2oxo1,2dihydroquinolin3yl)methyl...)
Affinity DataKi:  2.40E+4nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 無 assay buffer, 5 無 inhibitor solution, 5 無 of 10 nM enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-galactosidase(Streptococcus agalactiae (Firmicutes))
University of North Carolina At Chapel Hill

LigandPNGBDBM163639(Methyl 2({[(6ethyl2oxo1,2dihydroquinolin3yl)methyl...)
Affinity DataKi:  3.60E+4nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 無 assay buffer, 5 無 inhibitor solution, 5 無 of 10 nM enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed