BDBM163700 N-(5-((4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)carbamoyl)-2-methylphenyl)-5-(1-methyl-1H-pyrazol-4-yl)nicotinamide (5)::US10597387, Compound (I-9)
SMILES CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(NC(=O)c4cncc(c4)-c4cnn(C)c4)c3)cc2C(F)(F)F)CC1
InChI Key InChIKey=GZOONDJISKPFEJ-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 163700
Affinity DataIC50: 56nMAssay Description:The enzymatic activities DDR2 were tested in LanthaScreen binding assays. The protocol is available from Life Technologies.More data for this Ligand-Target Pair
Affinity DataIC50: 2.43nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Affinity DataIC50: 25.3nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:The enzymatic activities DDR2 were tested in LanthaScreen binding assays. The protocol is available from Life Technologies.More data for this Ligand-Target Pair