BDBM163721 3-Cyclohexyl-5-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}-4,5-dihydro-1,2,4-triazin-6(1H)-one (20)

SMILES Clc1cccc(N2CCN(CCCCC3NC(=NNC3=O)C3CCCCC3)CC2)c1Cl

InChI Key InChIKey=KEOZRZVKTWAHMM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 163721   

Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM163721(3-Cyclohexyl-5-{4-[4-(2,3-dichlorophenyl)piperazin...)
Affinity DataKi:  5nM ΔG°:  -11.3kcal/moleT: 2°CAssay Description:All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM163721(3-Cyclohexyl-5-{4-[4-(2,3-dichlorophenyl)piperazin...)
Affinity DataKi:  32nM ΔG°:  -10.2kcal/moleT: 2°CAssay Description:All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed