BDBM166589 US9073853, 148

SMILES COc1cc(CN(C[C@H]2CC[C@@H](CC2)C(O)=O)[C@H]2CCc3c2ccc(Cl)c3F)ccc1OCCN1C(=O)CCC1=O

InChI Key InChIKey=UWEVIRFQSCBLOI-OWHZGTRUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 166589   

TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM166589(US9073853, 148)
Affinity DataIC50:  26nMAssay Description:Displacement of [125I]-CXCL10 from human recombinant CXCR3 transfected in Flp-In-CHO cell membranes after 60 mins by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM166589(US9073853, 148)
Affinity DataIC50:  26nMAssay Description:Competition radioligand binding assays were performed to determine the in vitro potency of the newly synthesized, unlabeled test compounds to displac...More data for this Ligand-Target Pair
In DepthDetails US Patent