BDBM167912 N,N-diethylcarbamic acid-4-(5-hydroxy-6,7-dimethoxy-4-oxo-4H-1-benzopyran-2-yl)phenyl ester (7j)

SMILES CCN(CC)C(=O)Oc1ccc(cc1)-c1cc(=O)c2c(O)c(OC)c(OC)cc2o1

InChI Key InChIKey=BCPMGKFDBYFFIG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 167912   

TargetAcetylcholinesterase(Rattus norvegicus (rat))
Sichuan University

LigandPNGBDBM167912(N,N-diethylcarbamic acid-4-(5-hydroxy-6,7-dimethox...)
Affinity DataIC50:  570nMAssay Description:For rat AChE or BuChE inhibition assays, a reaction mixture (100 μL) containing acetylthiocholine iodide (1 mmol/L, 30 μL) (J&K Scientific)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Sichuan University

LigandPNGBDBM167912(N,N-diethylcarbamic acid-4-(5-hydroxy-6,7-dimethox...)
Affinity DataIC50:  2.26E+4nMAssay Description:For rat AChE or BuChE inhibition assays, a reaction mixture (100 μL) containing acetylthiocholine iodide (1 mmol/L, 30 μL) (J&K Scientific)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Sichuan University

LigandPNGBDBM167912(N,N-diethylcarbamic acid-4-(5-hydroxy-6,7-dimethox...)
Affinity DataIC50:  2.26E+4nMAssay Description:Inhibition of rat serum BChE using butyrylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Sichuan University

LigandPNGBDBM167912(N,N-diethylcarbamic acid-4-(5-hydroxy-6,7-dimethox...)
Affinity DataIC50:  570nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Sichuan University

LigandPNGBDBM167912(N,N-diethylcarbamic acid-4-(5-hydroxy-6,7-dimethox...)
Affinity DataIC50:  570nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed