BDBM169470 US9669034, 77 (rac)-4-[4-Fluoro-2-(prop-2-yn-1-yloxy)phenyl]-N-{3-[(S-methylsulfonimidoyl)methyl]phenyl}-1,3,5-triazin-2-amine::US9669034, 78 4-[4-Fluoro-2-(prop-2-yn-1-yloxy)phenyl]-N-{3-[(S-methylsulfonimidoyl)methyl]phenyl}-1,3,5-triazin-2-amine;enantiomer1::US9669034, 79 4-[4-Fluoro-2-(prop-2-yn-1-yloxy)phenyl]-N-{3-[(S-methylsulfonimidoyl)methyl]phenyl}-1,3,5-triazin-2-amine;enantiomer2

SMILES CS(=N)(=O)Cc1cccc(Nc2ncnc(n2)-c2ccc(F)cc2OCC#C)c1

InChI Key InChIKey=VNQSADCYOBYZMX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 169470   

TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM169470(US9669034, 77 (rac)-4-[4-Fluoro-2-(prop-2-yn-1-ylo...)
Affinity DataIC50:  15nMpH: 8.0 T: 2°CAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM169470(US9669034, 77 (rac)-4-[4-Fluoro-2-(prop-2-yn-1-ylo...)
Affinity DataIC50:  1.60E+3nMpH: 8.0 T: 2°CAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM169470(US9669034, 77 (rac)-4-[4-Fluoro-2-(prop-2-yn-1-ylo...)
Affinity DataIC50:  440nMpH: 8.0 T: 2°CAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM169470(US9669034, 77 (rac)-4-[4-Fluoro-2-(prop-2-yn-1-ylo...)
Affinity DataIC50:  580nMpH: 8.0 T: 2°CAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM169470(US9669034, 77 (rac)-4-[4-Fluoro-2-(prop-2-yn-1-ylo...)
Affinity DataIC50:  5nMpH: 8.0 T: 2°CAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM169470(US9669034, 77 (rac)-4-[4-Fluoro-2-(prop-2-yn-1-ylo...)
Affinity DataIC50:  9nMpH: 8.0 T: 2°CAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent