BDBM17085 3-chloro-N-{4-chloro-2-[(4-chlorophenyl)carbamoyl]phenyl}-4-[(4-methylpiperazin-1-yl)methyl]thiophene-2-carboxamide::Thiophene-Anthranilamide, 2::thiophene-containing non-amidine inhibitor, 31

SMILES CN1CCN(Cc2csc(C(=O)Nc3ccc(Cl)cc3C(=O)Nc3ccc(Cl)cc3)c2Cl)CC1

InChI Key InChIKey=FIZKTFMGWNHPMZ-UHFFFAOYSA-N

Data  5 KI

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 17085   

TargetProthrombin(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17085(3-chloro-N-{4-chloro-2-[(4-chlorophenyl)carbamoyl]...)
Affinity DataKi:  840nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17085(3-chloro-N-{4-chloro-2-[(4-chlorophenyl)carbamoyl]...)
Affinity DataKi:  910nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed