BDBM17357 1,2,4-Triazole Compound, 15::5-{[(2-methoxyphenyl)methyl]sulfanyl}-N-(2-methylphenyl)-4H-1,2,4-triazol-3-amine

SMILES COc1ccccc1CSc1nnc(Nc2ccccc2C)[nH]1

InChI Key InChIKey=INLCXQQDEZOCQH-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17357   

TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17357(1,2,4-Triazole Compound, 15 | 5-{[(2-methoxyphenyl...)
Affinity DataKi:  61nM ΔG°:  -9.74kcal/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed