BDBM173586 (2E)-1-(3-hydroxynaphthalen-2-yl)-3-(4-hydroxy-3-nitrophenyl) prop-2-en-1-one (4b)

SMILES Oc1ccc(\C=C\C(=O)c2cc3ccccc3cc2O)cc1[N+]([O-])=O

InChI Key InChIKey=NVZFUYHNWAYKQO-FNORWQNLSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 173586   

TargetPolyphenol oxidase 1 [N65D,S176D,K211T,P277A,P406L](Agaricus bisporus (Mushroom))
University of Technology Sydney

LigandPNGBDBM173586((2E)-1-(3-hydroxynaphthalen-2-yl)-3-(4-hydroxy-3-n...)
Affinity DataKi:  1.19E+4nM IC50:  2.56E+4nMpH: 6.8Assay Description:The mushroom tyrosinase inhibition activity of hydroxy naphthylchalcone compounds was measured using L-DOPA as substrate. The activity assay used 3 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed