BDBM173926 US9688645, 7-1

SMILES CC(C)[C@H]1COCCC(=O)Nc2ccc(C[C@@H](NC(=O)N[C@@H](CCCCN)C(O)=O)C(=O)N1)cc2

InChI Key InChIKey=VSIDOZVYCSEJST-XUVXKRRUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 173926   

TargetCarboxypeptidase B2(Homo sapiens (Human))
Schrodinger

Curated by ChEMBL
LigandPNGBDBM173926(US9688645, 7-1)
Affinity DataIC50:  22nMAssay Description:Inhibition of TAFIalpha in human plasma incubated for 15 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Schrodinger

Curated by ChEMBL
LigandPNGBDBM173926(US9688645, 7-1)
Affinity DataIC50:  22nMpH: 7.4 T: 2°CAssay Description:The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI Activity Kit from American Diagnostica (Pr. No. 874). This ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent