BDBM17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US11786535, Compound Indomethacin::US9271961, Indomethacin::indometacin
SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1
InChI Key InChIKey=CGIGDMFJXJATDK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 17638
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
St. Bartholomew'S and The Royal London School of Medicine and Dentistry
Curated by PDSP Ki Database
St. Bartholomew'S and The Royal London School of Medicine and Dentistry
Curated by PDSP Ki Database
Affinity DataKd: 1.02E+3nMAssay Description:Inhibitory activity of the synthesized compounds on COX-1 and COX-2 enzymes were evaluated at 40 μm using the COX Inhibitor Screening Assay Kit ...More data for this Ligand-Target Pair
Affinity DataKd: 700nMAssay Description:Binding affinity to human serum albuminMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
St. Bartholomew'S and The Royal London School of Medicine and Dentistry
Curated by PDSP Ki Database
St. Bartholomew'S and The Royal London School of Medicine and Dentistry
Curated by PDSP Ki Database
Affinity DataKd: 92nMAssay Description:Binding affinity to COX2 (unknown origin)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
St. Bartholomew'S and The Royal London School of Medicine and Dentistry
Curated by PDSP Ki Database
St. Bartholomew'S and The Royal London School of Medicine and Dentistry
Curated by PDSP Ki Database
Affinity DataKd: 253nMAssay Description:Binding affinity to COX1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 1.20E+5nMAssay Description:Binding affinity to human serum albumin assessed as dissociation constant and measured after 5 mins by MST assayMore data for this Ligand-Target Pair