BDBM17684 2-aminobenzimidazole, 9::N-methyl-4-({2-[(3-{[(2R)-1-methylpyrrolidin-2-yl]methoxy}-4-(trifluoromethyl)phenyl)amino]-1H-1,3-benzodiazol-5-yl}oxy)pyridine-2-carboxamide

SMILES CNC(=O)c1cc(Oc2ccc3nc(Nc4ccc(c(OC[C@H]5CCCN5C)c4)C(F)(F)F)[nH]c3c2)ccn1

InChI Key InChIKey=CNFXCXPJZGOMBX-QGZVFWFLSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17684   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM17684(2-aminobenzimidazole, 9 | N-methyl-4-({2-[(3-{[(2R...)
Affinity DataKi:  2nM ΔG°:  -11.7kcal/molepH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed