BDBM17687 2-aminobenzimidazole, 12::N-(3-{[(2R)-1-methylpyrrolidin-2-yl]methoxy}-4-(trifluoromethyl)phenyl)-5-(quinolin-4-yloxy)-1H-1,3-benzodiazol-2-amine

SMILES CN1CCC[C@@H]1COc1cc(Nc2nc3ccc(Oc4ccnc5ccccc45)cc3[nH]2)ccc1C(F)(F)F

InChI Key InChIKey=WATHVYRKWVIPDZ-LJQANCHMSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17687   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM17687(2-aminobenzimidazole, 12 | N-(3-{[(2R)-1-methylpyr...)
Affinity DataKi:  1nM ΔG°:  -12.1kcal/molepH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed