BDBM179878 US10231963, Table B.24::US10287250, Compound B.6::US10736890, Compound TABLE B.24::US10752592, Compound TABLE B.6::US11534436, Compound Table B.24::US9133125, Table B, Compound 6::US9656961, Example 00141

SMILES NC(=O)c1ccc2C[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CCC3)c2c1O

InChI Key InChIKey=AKNQIOIQJXBDSP-NJNPRVFISA-N

Data  7 KI  7 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 179878   

TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent
LigandPNGBDBM179878(US10231963, Table B.24 | US10287250, Compound B.6 ...)
Affinity DataKi:  0.120nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent
LigandPNGBDBM179878(US10231963, Table B.24 | US10287250, Compound B.6 ...)
Affinity DataIC50:  5nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent
LigandPNGBDBM179878(US10231963, Table B.24 | US10287250, Compound B.6 ...)
Affinity DataEC50:  2.10nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair
In DepthDetails US Patent