BDBM18012 trans,trans-4-arylpiperidine-based compound, 1
SMILES COC[C@@H](O)CO[C@@H]1CNC[C@H](OCc2cc(OC)c3ccccc3c2)[C@H]1c1ccc(OCCCOCc2ccccc2OC)cc1
InChI Key InChIKey=NSAUOOQLSGAVDH-YYZIUVEKSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 18012
Affinity DataIC50: 0.0670nMpH: 7.4 T: 2°CAssay Description:The renin assay utilized a tandem Green Flourescent Protein (tGFP) substrate that was hydrolyzed by human rennin. The tGFP substrate contained a nine...More data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0670nMAssay Description:Inhibition of human recombinant renin in bufferMore data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Inhibition of renin activity in human plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0670nMAssay Description:Inhibition of recombinant human reninMore data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0670nMAssay Description:Inhibition of human recombinant reninMore data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Inhibition of plasma renin (unknown origin)More data for this Ligand-Target Pair