BDBM180283 US9133162, Example 14

SMILES Cc1c(C(=O)Nc2ccc(Oc3ccnc4cc(OC(C)(C)CO)ccc34)c(F)c2)c(=O)n(-c2ccccc2)n1C

InChI Key InChIKey=FHGKCNHKMUMCLI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 180283   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM180283(US9133162, Example 14)
Affinity DataIC50:  27nMpH: 7.0 T: 2°CAssay Description:Met (h) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKSPGEYVNIEFG, 10 mM MgAcetate and [γ-33P-ATP] (specific activity approx. ...More data for this Ligand-Target Pair
In DepthDetails US Patent