BDBM18046 5-((4-methylphenyl)thio)-quinazoline 2,4-diamine, 1::5-[(4-METHYLPHENYL)SULFANYL]-2,4-QUINAZOLINEDIAMINE::5-[(4-methylphenyl)sulfanyl]quinazoline-2,4-diamine::5-[(4-methylphenyl)sulfanyl]quinazoline-2,4-diamine, 2c::CHEMBL83547::GW578

SMILES Cc1ccc(Sc2cccc3nc(N)nc(N)c23)cc1

InChI Key InChIKey=UOJFGEAPSYQDIP-UHFFFAOYSA-N

Data  2 KI  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 18046   

TargetDihydrofolate reductase(Escherichia coli)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM18046(5-((4-methylphenyl)thio)-quinazoline 2,4-diamine, ...)
Affinity DataKi:  73nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 30 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM18046(5-((4-methylphenyl)thio)-quinazoline 2,4-diamine, ...)
Affinity DataIC50:  820nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM18046(5-((4-methylphenyl)thio)-quinazoline 2,4-diamine, ...)
Affinity DataIC50:  310nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 30 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed