BDBM18064 3-[({[3,5-bis(trifluoromethyl)phenyl]methyl}sulfanyl)methanimidoyl]guanidine::amidinothiouronium, 19

SMILES NC(=N)NC(=N)SCc1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=KTMHBNXOHBHKBF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18064   

TargetDihydrofolate reductase(Escherichia coli)
University of Prince Edward Island

LigandPNGBDBM18064(3-[({[3,5-bis(trifluoromethyl)phenyl]methyl}sulfan...)
Affinity DataIC50:  5.60E+3nMpH: 7.0 T: 2°CAssay Description:The DHFR inhibition observed with each derivative was characterized by determination and comparison of the IC50 values. IC50 determinations were perf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed