BDBM180867 US9133180, 8

SMILES Cc1c[nH]c2cccc(-c3nc(C(N)=O)c(o3)-c3ccc(cc3)N3CCNC(C)(C)C3)c12

InChI Key InChIKey=AYVATFZLZLWIPA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 180867   

TargetAurora kinase A(Homo sapiens (Human))
Sareum

US Patent
LigandPNGBDBM180867(US9133180, 8)
Affinity DataIC50:  271nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure:1) Prepare indicated substrate in fr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Sareum

US Patent
LigandPNGBDBM180867(US9133180, 8)
Affinity DataIC50:  0.550nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure:1) Prepare indicated substrate in fr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Sareum

US Patent
LigandPNGBDBM180867(US9133180, 8)
Affinity DataIC50:  14.2nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure:1) Prepare indicated substrate in fr...More data for this Ligand-Target Pair
In DepthDetails US Patent