BDBM18449 2-({4-[(4-chlorophenyl)amino]-6-(pyrrolidin-1-yl)-1,3,5-triazin-2-yl}amino)ethan-1-ol::Triazine compound, 28::triazine scaffold, 30

SMILES OCCNc1nc(Nc2ccc(Cl)cc2)nc(n1)N1CCCC1

InChI Key InChIKey=XDVVBLXWYYYPSQ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18449   

TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Nih

LigandPNGBDBM18449(2-({4-[(4-chlorophenyl)amino]-6-(pyrrolidin-1-yl)-...)
Affinity DataKi:  4.23E+3nM ΔG°:  -7.23kcal/mole IC50:  7.73E+3nMpH: 5.9 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent resorufin from the substrate. The fluorescence was measured (excitation 570 nm, emiss...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Nih

LigandPNGBDBM18449(2-({4-[(4-chlorophenyl)amino]-6-(pyrrolidin-1-yl)-...)
Affinity DataIC50:  6.34E+3nMpH: 5.9 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent resorufin from the substrate. The fluorescence was measured (excitation 570 nm, emiss...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed