BDBM185581 US9156848, 2

SMILES C[C@@]1(CO[C@@H]([C@@H](N)C1)c1cc(F)ccc1F)N1Cc2c[nH]nc2C1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 185581   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Endotherm

Curated by ChEMBL
LigandPNGBDBM185581(US9156848, 2)
Affinity DataIC50:  34nMAssay Description:Inhibition of human DPP4 expressed in baculovirus expression system using Gly-Pro-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Endotherm

Curated by ChEMBL
LigandPNGBDBM185581(US9156848, 2)
Affinity DataIC50:  34.5nMpH: 7.5Assay Description:The utility of the compounds in accordance with the present invention as inhibitors of dipeptidyl peptidase-IV enzyme activity may be demonstrated by...More data for this Ligand-Target Pair
In DepthDetails US Patent