BDBM186127 US9163012, 44, Isomer 1::US9163012, 44, Isomer 2

SMILES COc1cnc(nc1)C1CCN(C1)C(=O)OC1C2CC3CC1CC(C3)(C2)C(N)=O

InChI Key InChIKey=SMSNTQOTWOOLSN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 186127   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM186127(US9163012, 44, Isomer 1 | US9163012, 44, Isomer 2)
Affinity DataIC50: >100nMT: 2°CAssay Description:Inhibition of microsomal preparations of 11.beta.-HSDl by compounds of the present invention, as described essentially previously (K. Solly, SS Mundt...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM186127(US9163012, 44, Isomer 1 | US9163012, 44, Isomer 2)
Affinity DataIC50:  3.11nMT: 2°CAssay Description:Inhibition of microsomal preparations of 11.beta.-HSDl by compounds of the present invention, as described essentially previously (K. Solly, SS Mundt...More data for this Ligand-Target Pair
In DepthDetails US Patent