BDBM186551 US9163021, 219::US9163021, 227

SMILES CC(CO)n1cc(C(=O)c2cncc(NC(=O)Cn3cc(cn3)C(F)(F)F)c2)c2cncc(F)c12

InChI Key InChIKey=WIQHTXCEWFSXNT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 186551   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM186551(US9163021, 219 | US9163021, 227)
Affinity DataIC50:  15.2nMAssay Description:Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat#62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor sou...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM186551(US9163021, 219 | US9163021, 227)
Affinity DataIC50:  24.3nMAssay Description:Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat#62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor sou...More data for this Ligand-Target Pair
In DepthDetails US Patent