BDBM186574 US10787472, Compound 10::US9163042, 10
SMILES Cc1cc(F)ccc1Oc1ccc(cc1C(=O)Nc1ccn(COP(O)(O)=O)c(=O)c1)C(F)(F)F
InChI Key InChIKey=OSCBQHPCUKAFNW-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 186574
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals
US Patent
Vertex Pharmaceuticals
US Patent
Affinity DataIC50: 86nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Vertex Pharmaceuticals
US Patent
Vertex Pharmaceuticals
US Patent
Affinity DataIC50: 86nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair