BDBM187187 US9670193, 3 N-methyl-N-(pyridin-4-ylmethyl)-5-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)pyrimidin-2-amine

SMILES CN(Cc1ccncc1)c1ncc(cn1)-c1noc(n1)C(F)(F)F

InChI Key InChIKey=LVHJLBFBNPSVRM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 187187   

TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM187187(US9670193, 3 N-methyl-N-(pyridin-4-ylmethyl)-5-(5-...)
Affinity DataIC50:  3.20E+3nMAssay Description:Human recombinant full length HDAC1 expressed in a baculovirus expression system was purchased from BPS BioSciences (San Diego, Calif., U.S.A.). The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM187187(US9670193, 3 N-methyl-N-(pyridin-4-ylmethyl)-5-(5-...)
Affinity DataIC50:  6.70E+3nMAssay Description:Human recombinant full length HDAC6 expressed in a baculovirus expression system was purchased from BPS BioSciences (San Diego, Calif., U.S.A.). The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 4 [2-1084](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM187187(US9670193, 3 N-methyl-N-(pyridin-4-ylmethyl)-5-(5-...)
Affinity DataIC50:  39nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent