BDBM189 (5R,6R)-1,5-dibenzyl-6-hydroxy-2,4-bis({[4-(hydroxymethyl)phenyl]methyl})-1,2,4-triazepan-3-one::(5R,6R)-2,4-Bis[(hydroxymethyl)benzyl]-1,5-dibenzyl-6-hydroxy-3-oxo-1,2,4-triazacycloheptane::Azacyclic Urea::Unnamed azacyclic urea

SMILES OCc1ccc(CN2[C@H](Cc3ccccc3)[C@H](O)CN(Cc3ccccc3)N(Cc3ccc(CO)cc3)C2=O)cc1

InChI Key InChIKey=ZGLNLADIKLQLDI-CZNDPXEESA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 189   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

LigandPNGBDBM189((5R,6R)-1,5-dibenzyl-6-hydroxy-2,4-bis({[4-(hydrox...)
Affinity DataKi:  0.220nM ΔG°:  -13.4kcal/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-GABA-Ser-Gln-Tyr-P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed