BDBM189051 US9169260, 317

SMILES COc1ncc(CN2CC(C2)c2cc(NC(=O)c3cnn4cccnc34)n(n2)-c2ccc(C)cc2)cn1

InChI Key InChIKey=XMFZNCZSIUZAAW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 189051   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM189051(US9169260, 317)
Affinity DataIC50: <1.00E+3nMpH: 7.2Assay Description:The kinase activity of IRAK-4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phos...More data for this Ligand-Target Pair
In DepthDetails US Patent