BDBM189525 US10213433, Compound 77::US11369599, Compound 77::US20240043404, Example 77::US9174982, 77
SMILES CC(C)(C)OC(=O)N1CCOCC1COc1ccc(cc1[N+]([O-])=O)S(=O)(=O)NC(=O)c1ccc(cc1Oc1cnc2[nH]ccc2c1)N1CCN(CC2=C(CC(C)(C)CC2)c2ccc(Cl)cc2)CC1
InChI Key
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 189525
Affinity DataKi: 0.213nM ΔG°: -13.2kcal/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
Affinity DataKi: 0.213nMAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 μM (2× starting concentration; 10% DMSO) and 10 μ...More data for this Ligand-Target Pair
Affinity DataKi: 0.213nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
Affinity DataKi: 0.213nMAssay Description:TR-FRET (Time-Resolved Fluorescence-Resonance-Energy-Transfer) assay.More data for this Ligand-Target Pair