BDBM190299 US10227346, Example 61::US10426135, Example 61::US9670201, 61 (R)-3-cyano-N-(3-(1-(cyclopentanecarbonyl)-2,2-dimethylpiperidin-4-yl)-1,4-dimethyl-1H-pyrrolo[2,3-b]pyridin-5-yl)-4-fluorobenzamide::US9920054, Example 61

SMILES Cc1c(NC(=O)c2ccc(F)c(c2)C#N)cnc2n(C)cc([C@@H]3CCN(C(=O)C4CCCC4)C(C)(C)C3)c12

InChI Key InChIKey=SVSJCHOSIKYNHV-OAQYLSRUSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 190299   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM190299(US10227346, Example 61 | US10426135, Example 61 | ...)
Affinity DataIC50:  15.2nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent