BDBM190661 PT166

SMILES CCCCCCc1cc(=O)c(Oc2ccccc2C)cn1C

InChI Key InChIKey=UMFLEDWOPZCDDL-UHFFFAOYSA-N

Data  2 KI  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 190661   

TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
University of Wuerzburg

LigandPNGBDBM190661(PT166)
Affinity DataKi:  2.70nMpH: 7.5Assay Description:Kinetics were performed on a Cary 100 spectrophotometer (Varian) at 20 °C. Reaction velocities were measured by monitoring the oxidation of NAD(P)H t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli)
University of Wuerzburg

LigandPNGBDBM190661(PT166)
Affinity DataKi:  7nMpH: 7.5Assay Description:Kinetics were performed on a Cary 100 spectrophotometer (Varian) at 20 °C. Reaction velocities were measured by monitoring the oxidation of NAD(P)H t...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Yersinia pestis (Enterobacteria))
University of Wurzburg

LigandPNGBDBM190661(PT166)
Affinity DataIC50:  1.80E+4nMAssay Description:IC50 values for the inhibition of wildtype and mutant forms of ypFabV were performed by adding varying concentrations of inhibitor dissolved in dimet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] [T276S](Yersinia pestis (Enterobacteria))
University of Wurzburg

LigandPNGBDBM190661(PT166)
Affinity DataIC50:  2.30E+4nMAssay Description:IC50 values for the inhibition of wildtype and mutant forms of ypFabV were performed by adding varying concentrations of inhibitor dissolved in dimet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed