BDBM191573 6-(3-fluorophenyl)pteridine-2,4,7-triamine (16)
SMILES Nc1nc(N)c2nc(c(N)nc2n1)-c1cccc(F)c1
InChI Key InChIKey=HEFCEQRTKCWRMZ-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 191573
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Max Planck Institute of Molecular Physiology
Max Planck Institute of Molecular Physiology
Affinity DataIC50: 3.33E+4nMAssay Description:Single-point measurements analyses and subsequent dose-dependent investigations of selected pteridine derivatives for inhibition of CK1α were pe...More data for this Ligand-Target Pair
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Max Planck Institute of Molecular Physiology
Max Planck Institute of Molecular Physiology
Affinity DataIC50: 1.44E+4nMpH: 7.5Assay Description:A stock solution of 5 % DMSO (BioReagent for molecular biology, Sigma Aldrich) in water was prepared. The CK1 substrate peptide RRKDLHDDEEDEAMSITA (J...More data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Max Planck Institute of Molecular Physiology
Max Planck Institute of Molecular Physiology
Affinity DataIC50: 6.18E+4nMpH: 7.5Assay Description:A stock solution of 5 % DMSO (BioReagent for molecular biology, Sigma Aldrich) in water was prepared. The CK1 substrate peptide RRKDLHDDEEDEAMSITA (J...More data for this Ligand-Target Pair