BDBM191632 US9182402, 2

SMILES Cc1ccc(OCc2nnc(NC(=O)Nc3cccc(Cl)c3)s2)cc1C

InChI Key InChIKey=PKUMGHOUAGUDQS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 191632   

TargetSerine protease hepsin(Homo sapiens (Human))
Fred Hutchinson Cancer Research Center

US Patent
LigandPNGBDBM191632(US9182402, 2)
Affinity DataIC50:  760nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Bos taurus (Bovine))
Fred Hutchinson Cancer Research Center

US Patent
LigandPNGBDBM191632(US9182402, 2)
Affinity DataIC50: >2.00E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrypsin(Sus scrofa)
Fred Hutchinson Cancer Research Center

US Patent
LigandPNGBDBM191632(US9182402, 2)
Affinity DataIC50: >2.00E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In DepthDetails US Patent