BDBM194495 US9200020, Table 3 compound 4
SMILES OP(O)(=O)CCN(CCn1c[nH]c2c1nc[nH]c2=O)CC#N
InChI Key InChIKey=JOZQFWHAFKGCKZ-UHFFFAOYSA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 194495
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University of Queensland
US Patent
The University of Queensland
US Patent
Affinity DataKi: 3.50E+4nM ΔG°: -6.32kcal/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979
Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in
vitr...More data for this Ligand-Target Pair
Affinity DataKi: 4.70E+4nM ΔG°: -6.14kcal/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979
Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in
vitr...More data for this Ligand-Target Pair
TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
The University of Queensland
US Patent
The University of Queensland
US Patent
Affinity DataKi: >2.50E+5nM ΔG°: >-5.11kcal/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979
Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in
vitr...More data for this Ligand-Target Pair