BDBM195 (5R,6R)-1,5-dibenzyl-2-(cyclopropylmethyl)-6-hydroxy-4-[(4-hydroxy-3-methoxyphenyl)methyl]-1,2,4-triazepan-3-one::Azacyclic Urea::Unnamed azacyclic urea
SMILES COc1cc(CN2[C@H](Cc3ccccc3)[C@H](O)CN(Cc3ccccc3)N(CC3CC3)C2=O)ccc1O
InChI Key InChIKey=ZXMNXYSILSXVSY-IXCJQBJRSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 195
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories
Abbott Laboratories
Affinity DataKi: 0.0620nM ΔG°: -14.1kcal/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-GABA-Ser-Gln-Tyr-P...More data for this Ligand-Target Pair